The present volume summarizes current research on type 2 diabetes, its etiology, pathogenesis and long-term vascular and neurological consequences, with special emphasis on molecular and biochemical mechanisms. Alterations in insulin secretion are comprehensively treated, focusing on the role of glucokinase as glucose sensor. Moreover, insulin action is analyzed with regard to both nonoxidative glucose utilization and glucose oxidation. Concerning the complications in chronic diabetes, topics covered include the effects of high glucose concentration on cellular and endothelial functions and on the glucose phosphorylation rate in non-insulin-sensitive tissues. Furthermore, the role of oxidative stress and advanced glycation end products as well as the significance of alterations in lipoprotein structure are considered. Finally, the pericyte loss in retinopathy and microalbuminuria as related to cardiovascular risk are discussed. Taken as a whole, the contributions included in this book represent a large body of information that will be of great interest to diabetologists, endocrinologists and internists interested in both the basic and clinical aspects of diabetes and its complications.
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Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed insulin secretion in both healthy individuals and in patients with type 2 diabetes. Because of the risk associated with progression from insulin resistance to diabetes and cardiovascular complications increases along a continuum, we included several chapters on the damage of endothelial cells in type 2 diabetes and genetic influences on endothelial cell dysfunction. Cardiovascular complications occur at a much lower glucose levels, thus a review on the oral glucose tolerance test compared to other methods was included. The medical conditions associated with type 2 diabetes such as pancreatic cancer, sarcopenia and sleep disordered breathing with diabetes were also discussed. The book concludes with several chapters on the treatments for this disease offering us hope in prevention and successful alleviation of the co-morbidities associated with obesity and type 2 diabetes.
Type 2 diabetes is estimated to affect 120 million people worldwide- and according to projections from the World Health Organization this number is expected to double over the next two decades. Novel, cost-effective strategies are needed to reverse the global epidemic of obesity which is driving the increased occurrence of type 2 diabetes and to less the burden of diabetic vascular complications. In the current volume, Topics in the Prevention, Treatment and Complications of Type 2 Diabetes, experts in biology and medicine from four different continents contribute important information and cutting-edge scientific knowledge on a variety of topics relevant to the management and prevention of diabetes and related illnesses.
This book is aimed at clinicians, internists, postgraduate students who want to keep abreast of the recent advances in understanding of all micro and macrovascular complications of diabetes. A crisp and concise quick reference guide to all the complications seen in patients with diabetes mellitus. A easy-to-read format, supplemented with clinical pearls, fast facts, and algorithms, enables rapid understanding of key aspects of pathogenesis and management of complications of diabetes. The book will be very useful to physicians as well as students to serve as an important resource to enrich their practice of diabetes care. All complications of diabetes have been comprehensively covered with equal emphysis on acute metabolic and chronic microvascular and macrovascular complications.
3-2-1 CODE IT! 4E is the premier, easy-to-use medical coding guide for both beginners and experienced professionals. This best-selling textbook begins with diagnosis coding, then builds on this foundation through in-depth instruction on ICD-9-CM, CPT, and HCPCS Level II coding. 3-2-1 CODE IT! 4E prepares readers better than ever for earning a coding credential by using the latest code sets, conventions, and guidelines. This edition also features strategic tips on career advancement that readers will find helpful for years to come. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Effectively avoiding, recognizing, and managing complications is integral to your operative success. Let a multidisciplinary team of experts in otolaryngology, plastic surgery, oral and maxillofacial surgery, and general surgery guide you through the full range of complications associated with every type of head and neck procedure . . . so you will be equipped to produce the most favorable outcomes for even the most challenging cases! Expert, comprehensive, multidisciplinary coverage of head and neck complications helps you to safely incorporate new surgical techniques into your practice. An emphasis on complication prevention and recognition assists you in avoiding the "complication cascade." Coverage of both acute and long-term care of patients with head and neck complications prepares you to make effective choices in both instances. A new "Quality of Life" section examines the controversies that often surround selecting one procedure over another, illuminating why certain procedures aren't always best for some patients. A new section on complications of facial plastic and reconstructive surgery equips you to perform these techniques with greater confidence. A consistent, practical chapter format helps you focus on key clinical and surgical considerations. A new, more cohesive full-color illustration program richly captures visual nuances of clinical presentation and operative technique. A bonus CD-ROM allows you to use all of the images from the book in electronic presentations.
Neurologic side effects of cancer therapy can inhibit treatment, can be dose-limiting and can diminish quality-of-life. Neurotoxicity related to cancer therapy is a common problem in oncology practice and in clinical neurology. Recognition of neurologic complications of anticancer therapy is necessary due to potential confusion with metastatic disease, paraneoplastic syndromes or comorbid neurologic disorders that do not require reduction or discontinuation of therapy. Neurologic Complications of Cancer Therapy provides comprehensive coverage of the recognition and management of neurologic symptoms related to cancer therapy. The book includes sections on systemic therapy discussed by both agent and adverse event. The section on adverse events is particularly valuable to clinicians, allowing them to consult by symptom in cases where multiple agents have been administered and the source of the complication is uncertain. The systemic therapy section includes coverage of immunologic agents, biologics, and targeted therapies. The book also features sections on the complications of radiation therapy, complications of surgery and high-dose chemotherapy, and stem cell transplantation. Neurologic Complications of Cancer Therapy Features: A widely recognized team of editors Systemic therapy covered by therapeutic agent and by adverse event, enabling a "problem-oriented" approach for the clinician Coverage of newer modalities including immunologic agents, biologics, and targeted therapies Complete sections on complications of radiation therapy, surgery, high-dose chemotherapy, and stem-call transplantion
Complications of Urologic Surgery: Prevention and Management, 4th Edition, by Samir S. Taneja, MD, is a urology resource that presents current management strategies—with an emphasis on prevention—for the most effective patient care. Recognized leaders in the field address both office-based complications as well as common and uncommon surgical complications arising from open and minimally invasive urologic surgery, to equip you to handle a wide range of situations. • Emphasizes prevention over quick fixes for more effective handling of urologic complications and better patient outcomes. • Covers both acute and long-term care of patients with urologic complications to equip you to manage more cases. • Features the work of recognized leaders in urology for guidance you can trust. • Offers up-to-date management approaches of urologic complications to help you stay on top of issues and controversies as you incorporate new surgical techniques into your practice. • Presents a new section on minimally invasive complications that address the challenges arising from laparoscopic and robotic techniques. • Includes a discreet medical complications section that enables you to stay up to date with this rapidly changing area of urology and understand the risks and benefits of the newest hormone and chemotherapeutic regimens. • Uses Key Points at the top of each chapter to help you find information quickly and study for the boards more efficiently. • Features a new, four-color format and illustrations that highlight important points within the text.
Interventional cardiologists are able to perform minimally invasive procedures, such as angioplasty and stenting, due to imaging technologies that allow them to see inside the heart and blood vessels without open surgery. Such imaging often requires injection of contrast media, which are generally safe, but for some patients with drug sensitivities or compromised kidney function, contrast-induced nephropathy (CIN) can result. CIN is a major complication that can increase in-hospital mortality. This issue of Interventional Cardiology Clinica addresses the management, treatment, and prevention of renal complications in the catheterization laboratory.